Diet Linked to Arthritis

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Having a bad diet may increase your chances of developing osteoarthritis. Scientists have long thought the condition was tied to obesity and excessive stress placed on the joints, reports MedicalDaily.com. But in a new study, a team from the University of Rochester Medical Center found that a high-fat Western diet caused mice not only to gain weight but also to develop systemic inflammation and an imbalance in their gut microbiome: Their colons had high levels of harmful bacteria and hardly any beneficial “probiotic” bacteria. When the researchers tore cartilage in the rodents’ knees to trigger osteoarthritis, the disease progressed more rapidly in the obese mice. When they then treated these mice with a probiotic to restore their gut microbiome, the rodents had less inflammation and their joint health improved. Study author Eric Schott says his team’s findings “set the stage to develop therapies that target the microbiome and actually treat the disease.”

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