Scientists believe they have discovered why psychological stress can lead to physical pain. A research team at Carnegie Mellon University in Pittsburgh found that chronic psychological stress is associated with the body losing its ability to regulate the inflammatory response. Published in the Proceedings of the National Academy of Sciences today, the research shows for the first time that the effects of psychological stress on the body’s ability to regulate inflammation can lead to the development and progression of disease. Sheldon Cohen, professor of psychology at the university’s Dietrich College of Humanities and Social Sciences, said prolonged stress alters the effectiveness of cortisol to regulate the inflammatory response because it decreases tissue sensitivity to the hormone. Specifically, immune cells become insensitive to cortisol’s regulatory effect and in turn runaway inflammation is thought to promote the development and progression of many diseases. He said: “Inflammation is partly regulated by the hormone cortisol and when cortisol (Read More)
Inflammation is the most common cause of pain. Relieve inflammation and you relieve pain. Inflammation is caused by the release of PGE1 prostaglandin and is sustained by an enzyme called cyclooxygenase 2 (COX2). It is interesting that cancer cells are surrounded by an abnormally heavy concentration of COX2 enzymes. If one could inhibit COX2 enzymes, they could control inflammation and possibly cancer. (This is substantiated by evidence of less cancers among chronic aspirin users). Many years ago drug companies found that aspirin inhibited COX2 but at the same time inhibited COX2 which is a protective prostaglandin for the lining of the digestive tract and blood vessels. Without adequate COX2 you can have ulcers and leaking of the blood vessels. So, for temporary use, aspirin is fine but extended use causes serious side effects. Then came the “miracle” of the COX2 inhibitors – Vioxx, Bextra, Celebrex and others in the market. (Read More)
We’ve all read the signs of a heart attack listed on posters in the hospital waiting room. But what if there were other, earlier signs that could alert you ahead of time that your heart was in trouble? It turns out there are. Researchers have done a lot of work in recent years looking at the signs and symptoms patients experienced in the months or even years leading up to a heart attack. “The heart, together with the arteries that feed it, is one big muscle, and when it starts to fail the symptoms can show up in many parts of the body,” says cardiologist Jonathan Goldstein of St. Michael’s Medical Center in Newark, New Jersey.
Inflammation is now recognized as an overwhelming burden to the healthcare status of our population and the underlying basis of a significant number of diseases. The elderly generally bear the burden of morbidity and mortality, which may be reflective of elevated markers of inflammation resulting from decades of lifestyle choices. Lower cancer rates are associated with diets high in fiber, fruits, vegetables, and tea. AD and PD may be prevented or treated with aggressive vitamin E, curcumin, acetylcarnitine, and catechin supplementation.
A gate is a good analogy for understanding bone joint degeneration. A new gate moves free and easy, much like healthy joints. In time, as the joint and gate hinge begin to breakdown or rust, movement becomes restricted and slower. With proper nutritional supplementation and chiropractic care, your joints can maintain proper motion. For the gate, try WD40. :-)
It starts with Curcumin A recent UCLA research review discusses the protective factors of curcumin (an extract of turmeric root), one of the main ingredients of curry powder, against Alzheimer’s disease. Substantial evidence suggests that it may inhibit destructive plaque accumulation in the brain, as well as break up existing plaques.
We recently wrote about promising research linking Vitamin D and the reduction of chronic pain. Now researchers have found the molecular pathway through which vitamin D inhibits inflammation. Researchers from the National Jewish Health Center in Denver reported their findings in the March issue of The Journal of Immunology. These new findings are another promising validation of the amazing properties of vitamin D.
Curcumin (found in a concentrated form as curcuminoids in Relevit – our all-natural anti-inflammatory formula) is one of the most amazing herbs in assisting the body in dealing with chronic pain and inflammation. A recent study further validates this powerful antioxidant and anti-inflammatory all rolled into one.