New diagnosis of Alzheimer’s disease cases continue to mount at an unprecedented rate, threatening both the lives of those suffering from this dreaded illness and the health care system itself, as billions are spent to care for the millions suffering from this lifestyle-mediated disease.
New hope is now offered by scientists from the University of California publishing in the Journal of Alzheimer’s Disease, as they have identified the specific intracellular mechanism regulated by vitamin D3 that may help the body clear the brain of amyloid beta.
There has been scant evidence in the past to show that vitamin D and the curry-derived compound, curcumin help to prevent Alzheimer’s dementia. Researchers now provide solid research-based science to explain the precise pathway used by these two natural substances to help stimulate the immune system to activate key genes involved in clearing the amyloid-beta protein.
Vitamin D3 and Curcumin Works Together to Clear Deadly Brain Plaques.
Our Best-Selling, Proprietary, Concentrated Curcuminoid Based Formula. Chiropractor Recommended!View in Store
Proprietary Vitamin D3 Formula - The Sunshine Vitamin - Supports Bone, Immunity, Heart & Brain HealthView in Store
Powerful antioxidant that protects cells, reduces inflammation naturally and supports healthy cognitive function.View in Store
You are familiar with our best-selling Relevit with a concentrated form of curcumin – curcuminoids – that assist the body in reducing inflammation. In addition, we have Liposomal Curcumin that maximizes your absorption of this critical nutrient for brain health. Dense Bone – formulated with 2,000 IU of vitamin D3 in every capsule as well as strontium and vitamin K2 for better absorption assists those who seek to don’t get enough sun or need to increase their vitamin D intake.
Ernest from Maryland on Relevit:
“An amazing product which taken as directed relives knee pain, shoulder pain and those little aches and pains from regular exercise. My wife and I both use this product. Love it.”
William from Nevada on Dense Bone:
“I have been using this product for two years. I am a strong advocate of the need for vitamin D supplements added to one’s diet. This product does so with great success and definitely helps me maintain good health and a sense of well-being.”
Chief study author, Dr. Milan Fiala noted, “This new study helped clarify the key mechanisms involved, which will help us better understand the usefulness of vitamin D3 and curcumin as possible therapies for Alzheimer’s disease.” Prior research has suggested a synergistic effect between the two compounds and clearance of deadly protein tangles, but no action pathway has ever been postulated until now.
To test their hypothesis, scientists took blood samples from a group of currently diagnosed Alzheimer’s disease patients and a control group of healthy volunteers. They then isolated the immune-stimulating component of the white blood cells called macrophages. These special cells are known to target and eliminate amyloid fibrils and other waste products that accumulate in the brain before they manifest into detectable disease conditions.
Include Regular Sun Exposure or Supplement Vitamin D3 and Curcumin to Prevent Alzheimer’s Disease
Researchers then incubated some of the extracted immune cells for a 24 hour period in a solution containing the active form of vitamin D3 (1a, 25-dihydroxyvitamin D3). Other cells were exposed to a standardized curcumin extract. Past studies have shown that there are two types of macrophages, Type I and Type II that independently perform different functions, yet must work together to effectively remove amyloid protein in the brain.
The scientists found that Type I macrophage activity is greatly enhanced with optimal saturation of vitamin D3, and Type II immune cells are supported by the presence of curcumin. Researchers found that the action of both Type I and II macrophages are greatly enhanced by the synergistic application of vitamin D3 and curcumin together. Dr. Fiala concluded, “Our findings demonstrate that active forms of vitamin D3 (and curcumin) may be an important regulator of immune activities of macrophages in helping to clear amyloid plaques.”
Proof positive now exists to support maintaining optimal blood saturation levels (50 to 70 ng/mL) of vitamin D as measured using the simple and inexpensive 25(OH)D test. Most people will need to supplement with 5,000 to 7,000 IU of vitamin D3 per day or rely on sun exposure to obtain ideal levels. Adding curcumin to your regular diet using natural curry-enriched foods or supplementing (300 to 500 mg per day standardized to 95% total curcuminoids) will provide a synergistic effect shown to help clear brain tangles and prevent Alzheimer’s dementia.